Is Polysialylated NCAM Not Only a Regulator during Brain Development But also during the Formation of Other Organs?
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Is Polysialylated NCAM Not Only a Regulator during Brain Development But also during the Formation of Other Organs?
In mammals several cell adhesion molecules are involved during the pre- and postnatal development of all organ systems. A very prominent member of this family is the neural cell adhesion molecule (NCAM). Interestingly, NCAM can be a target for a special form of posttranslational modification: polysialylation. Whereas nearly all extracellular proteins bear mono-sialic acid residues, only a very ...
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ژورنال
عنوان ژورنال: Biology
سال: 2017
ISSN: 2079-7737
DOI: 10.3390/biology6020027